Cytokines and Growth Factors
细胞因子是由免疫细胞及多种组织细胞合成、分泌的小分子可溶性蛋白或多肽,是细胞间传递信号的关键信使。它们通过结合靶细胞表面受体,调控免疫应答、炎症反应、细胞增殖、分化与凋亡,参与机体抗感染、抗肿瘤、组织修复等生理过程。常见类型包括白细胞介素、干扰素、肿瘤坏死因子、集落刺激因子、趋化因子等。细胞因子作用具有多效性、重叠性、协同性和拮抗性,异常表达会引发炎症、自身免疫病、过敏等疾病,也是免疫治疗、疫苗研发的重要靶点。
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