Analytical Data
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基因名
DAPP1
- Application
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别名
BAM32; B lymphocyte adapter protein Bam32; B-cell adapter molecule of 32 kDa; Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide
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种属
Mouse
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表达系统
E. coli
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标签
N-His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9QXT1
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表达区间
Met1~Lys280
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分子量
36.0kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
DAPP1, or Dual Adapter for Phosphotyrosine-binding 1, is a protein that plays a crucial role in various cellular signaling pathways, particularly those linked to immune responses and cell activation. Its primary function involves binding to phosphorylated tyrosine residues on target proteins, which is essential for transmitting signals initiated by receptor activation. Research into DAPP1 has gained traction due to its involvement in hematopoietic cell development and its potential implications in diseases such as cancer and autoimmune disorders. Specifically, studies have demonstrated that DAPP1 regulates the activation of T cells and B cells, modulating immune responses and maintaining cellular homeostasis. Additionally, alterations in DAPP1 expression or function have been correlated with the progression of immune-related diseases, thus positioning it as a potential biomarker or therapeutic target. The recombinant expression of DAPP1 provides a platform for elucidating its molecular mechanisms and interactions within signaling pathways, as well as for screening potential inhibitors or modulators that could influence its activity in pathological conditions. Consequently, understanding DAPP1 at the molecular level could facilitate the development of novel strategies for the treatment of diseases where immune signaling is disrupted.
