Analytical Data
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基因名
ATP13A3
- Application
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别名
AFURS1; ATPase Family Homolog Up Regulated In Senescence Cells; Probable cation-transporting ATPase 13A3
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种属
Human
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表达系统
E. coli
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标签
N- His & GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9H7F0
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表达区间
Met50~Ser202
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分子量
48kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ATP13A3 is a member of the P-type ATPase family, which is implicated in various cellular processes, including ion transport and cellular homeostasis. This protein is particularly interesting due to its association with neurological disorders, such as Kufor-Rakeb syndrome and other forms of parkinsonism. ATP13A3 is believed to contribute to the regulation of cellular zinc levels and lysosomal function, which are critical for neuronal health and function. The study of ATP13A3 recombinant proteins has gained momentum in recent years as researchers aim to elucidate its structure, function, and potential pathogenic mechanisms. By expressing and purifying recombinant ATP13A3, scientists can investigate its biochemical properties, interaction with metal ions, and effects on cellular signaling pathways. Understanding the role of ATP13A3 in cellular physiology and its implications in disease could lead to the development of therapeutic strategies targeting its dysfunction, thereby providing insight into neurodegenerative processes. Given the growing interest in lysosomal function and neurodegeneration, research on ATP13A3 recombinant proteins represents a pivotal area of study that holds promise for advancing our knowledge of these critical biological pathways.
