Analytical Data
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Gene name
Mettl10
- Application
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Alternative Names
Methyltransferase-like protein 10;Protein-lysine N-methyltransferase Mettl10
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Species
Mouse
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Source
Yeast
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Tag
C- His-Myc
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9D853
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Expression Region
1-244aa
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Molecular Weight
30.3 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Mettl10, a member of the METTL family, has garnered significant interest in recent years due to its potential role in RNA modification and gene regulation. As a methyltransferase, Mettl10 is believed to be involved in the methylation of adenosine residues in RNA, a process critical for various cellular functions, including mRNA stability, splicing, and translation. Research indicates that dysregulation of Mettl10 expression may be linked to several pathologies, including cancers and neurological disorders, emphasizing its importance in maintaining cellular homeostasis. Advances in high-throughput sequencing and bioinformatics have enabled researchers to unveil the global impact of Mettl10 on the transcriptome, leading to a better understanding of its biological functions. Furthermore, studies have demonstrated that Mettl10 interacts with various cellular pathways, suggesting a multifaceted role in modulating gene expression in response to environmental cues. As such, exploring the mechanisms underlying Mettl10's action could provide valuable insights into its potential as a therapeutic target, paving the way for novel strategies in treating diseases associated with RNA dysregulation. Overall, the ongoing research into Mettl10 is set to contribute significantly to the broader field of epitranscriptomics, enhancing our understanding of how RNA modifications orchestrate cellular fate and function.
