Analytical Data
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Gene name
AK3
- Application
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Alternative Names
AK3；AK3L1；AK6；AKL3L；GTP:AMP phosphotransferase AK3. mitochondrial
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9UIJ7
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Expression Region
1-227aa
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AA Sequence
Adenylate kinase 3 alpha-like 1; Adenylate kinase 3; Adenylate kinase 3. formerly; adenylate kinase 6. adenylate kinase 3 like 1; AK 3; AK3; AK3. formerly; AK3L1; AK4; AK4. mouse. homolog of; AK6; AKL3L; AKL3L1; FIX; GTP:AMP phosphotransferase; GTP:AMP phosphotransferase. mitochondrial; KAD3_HUMAN; mitochondrial; OTTHUMP00000021015; OTTHUMP00000021016; RP11 6J24.4
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Molecular Weight
32.6 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The AK3 protein, known as adenylate kinase 3, plays a crucial role in cellular energy metabolism by catalyzing the conversion of ATP and AMP to ADP, thus maintaining the balance of nucleotide levels within the cell. Recent studies have highlighted its significance in various physiological processes, including muscle contraction, signal transduction, and apoptosis. Dysregulation of AK3 has been implicated in several diseases, including cancer, where it may contribute to altered energy homeostasis and cellular proliferation. Research has also indicated that AK3 may be involved in the mitochondrial dynamics and cellular response to stress. As a result, the recombinant expression and characterization of AK3 have gained attention in the field of molecular biology and biotechnology. Investigating AK3 through recombinant techniques allows for in-depth studies of its structure-function relationship and its interactions with other cellular components. Understanding these dynamics could potentially lead to novel therapeutic strategies targeting AK3 in disease contexts, making it a promising target for drug development and intervention strategies aimed at restoring metabolic balance.
