Cat: PA1000-295DB

Recombinant Human BASP1 Protein,His

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Analytical Data

  • Gene name

    BASP1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    BASP1;NAP22;Brain acid soluble Protein 1

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    P80723

  • Expression Region

    1-227aa

  • AA Sequence

    MGSSHHHHHH SSGLVPRGSH MGSMGGKLSK KKKGYNVNDE KAKEKDKKAE GAATEEEGTP KESEPQAAAE PAEAKEGKEK PDQDAEGKAE EKEGEKDAAA AKEEAPKAEP EKTEGAAEAK AEPPKAPEQE QAAPGPAAGG EAPKAAEAAA APAESAAPAA GEEPSKEEGE PKKTEAPAAP AAQETKSDGA PASDSKPGSS EAAPSSKETP AATEAPSSTP KAQGPAASAE EPKPVEAPAA NSDQTVTVKE

  • Molecular Weight

    25 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

BASP1 (Brain Abundant, Membrane Anchored Protein 1) is a member of the BASP protein family, known for its roles in membrane dynamics and cellular signaling. The protein is predominantly expressed in the brain and has been implicated in various neurobiological processes, including synaptic transmission, plasticity, and neuronal survival. Recent studies have highlighted BASP1's involvement in modulating lipid interactions and membrane composition, which are critical for maintaining cellular homeostasis and facilitating signal transduction. Additionally, BASP1 has been associated with neurodegenerative diseases, making it an attractive target for therapeutic interventions. Research into recombinant BASP1 protein aims to elucidate its functional mechanisms at the molecular level, particularly in the context of neuronal health and disease. By producing and characterizing recombinant BASP1, scientists can investigate its binding properties, identify interacting partners, and explore its effects on cellular pathways. This research could pave the way for new insights into the roles of BASP1 in the nervous system and its potential as a biomarker or therapeutic target in neurodegenerative disorders. Overall, the study of recombinant BASP1 protein serves as a vital foundation for advancing our understanding of brain function and the molecular underpinnings of neurological diseases.

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