Analytical Data
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基因名
HDGFL1
- Application
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别名
HDGFL1;PWWP1;Hepatoma-derived growth factor-like Protein 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q5TGJ6
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表达区间
1-251aa
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氨基酸序列
MSAYGMPMYK SGDLVFAKLK GYAHWPARIE HMTQPNRYQV FFFGTHETAF LSPKRLFPYK ECKEKFGKPN KRRGFSAGLW EIENNPTVQA SDCPLASEKG SGDGPWPEPE AAEGDEDKPT HAGGGGDELG KPDDDKPTEE EKGPLKRSAG DPPEDAPKRP KEAAPDQEEE AEAERAAEAE RAAAAAAATA VDEESPFLVA VENGSAPSEP GLVCEPPQPE EEELREEEVA DEEASQEWHA EAPGGGDRDS L
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HDGFL1 (High-Grade Gleason Score-Associated Factor 1) is a protein that has garnered attention in cancer research, particularly in the context of prostate cancer. This protein is believed to play a significant role in tumor progression and metastasis, particularly in high-grade tumors characterized by aggressive behavior and poor patient prognosis. Studies have shown that HDGFL1 expression is upregulated in cancer tissues compared to normal tissues, suggesting its potential as a biomarker for diagnosis and prognosis. Furthermore, HDGFL1 is thought to be involved in various cellular processes, including cell proliferation, apoptosis, and the regulation of transcription factors, which may contribute to the malignant characteristics of cancer cells. Research has also indicated that targeting HDGFL1 might offer new therapeutic avenues for treatment, as its inhibition could effectively suppress tumor growth and enhance the sensitivity of cancer cells to standard therapies. Thus, understanding the molecular mechanisms underlying HDGFL1's function and its role in cancer biology is crucial for the development of innovative strategies aimed at improving clinical outcomes for patients with high-grade tumors. As ongoing studies continue to explore the implications of HDGFL1 in cancer, this protein stands as a promising subject for further investigation in the quest for effective cancer management and personalized treatment approaches.
