Analytical Data
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Gene name
MRPL2
- Application
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Alternative Names
MRPL2;Large ribosomal subunit Protein uL2m
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q5T653
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Expression Region
84-202aa
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AA Sequence
MGSSHHHHHH SSGLVPRGSH MGSGRDHTGR IRVHGIGGGH KQRYRMIDFL RFRPEETKSG PFEEKVIQVR YDPCRSADIA LVAGGSRKRW IIATENMQAG DTILNSNHIG RMAVAAREGD AHPLGALPVG TLINNVESEP GR
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Molecular Weight
16 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
MRPL2 (Mitochondrial Ribosomal Protein L2) is a crucial component of the mitochondrial ribosome, playing a pivotal role in mitochondrial protein synthesis and the overall functionality of mitochondria. Mitochondria are essential organelles responsible for energy production, cellular metabolism, and regulation of apoptotic pathways. Dysregulation or mutations in mitochondrial proteins, including MRPL2, can lead to various mitochondrial diseases, which often manifest as metabolic disorders, neurodegeneration, and other serious health conditions. The study of MRPL2 recombinant proteins is vital for understanding its structure-function relationship and its role in mitochondrial biogenesis and homeostasis. By producing recombinant MRPL2, researchers can investigate its biochemical properties, interactions with other mitochondrial components, and the impact of specific mutations on its activity. This research can also provide insights into potential therapeutic targets for mitochondrial diseases. Furthermore, recombinant MRPL2 can be utilized in studies exploring protein expression, folding, and the mechanisms underlying mitochondrial translation, thereby deepening our understanding of mitochondrial dynamics and their implications in human health and disease. Overall, the investigation of MRPL2 through recombinant protein studies is a significant step towards elucidating the complexities of mitochondrial functions and their contributions to cellular health.
