Analytical Data
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基因名
RAB24
- Application
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别名
RAB24;Ras-related Protein Rab-24
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q969Q5
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表达区间
1-227aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMGSHMSGQRVDVKVVMLGKEYVGKTSLVER YVHDRFLVGPYQNTIGAAFVAKVMSVGDRTVTLGIWDTAGSERYEAMSRI YYRGAKAAIVCYDLTDSSSFERAKFWVKELRSLEEGCQIYLCGTKSDLLE EDRRRRRVDFHDVQDYADNIKAQLFETSSKTGQSVDELFQKVAEDYVSVA AFQVMTEDKGVDLGQKPNPYFYSCCHH
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分子量
26 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RAB24, a member of the RAS oncogene family, is a small GTPase that plays a crucial role in intracellular membrane trafficking and cellular signaling processes. It is particularly involved in the regulation of autophagy and endosomal pathways, which are essential for cellular homeostasis and response to stress. Recent studies have implicated RAB24 in various physiological and pathological processes, including cancer progression, immune response, and neurodegenerative diseases. The interest in RAB24 as a potential therapeutic target has grown, as its dysregulation is associated with tumorigenesis and metastasis. Research on recombinant RAB24 proteins aims to elucidate its specific functions and interactions within cellular pathways. This involves the production of tagged RAB24 proteins to study their localization, binding partners, and mechanistic roles in vivo and in vitro. Understanding RAB24’s molecular mechanisms can provide insights into its contributions to disease and inform the development of novel therapeutic strategies targeting this GTPase. Therefore, studying recombinant RAB24 proteins is not only vital for comprehending fundamental cell biology but also holds promise for translating findings into clinical applications.
