Analytical Data
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基因名
NARFL
- Application
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别名
CIAO3; NARFL; PRNCytosolic iron-sulfur assembly component 3; Cytosolic Fe-S cluster assembly factor NARFL; Iron-only hydrogenase-like protein 1; IOP1; Nuclear prelamin A recognition factor-like protein; Protein related to Narf
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9H6Q4
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表达区间
2-476 aa
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氨基酸序列
ASPFSGALQ LTDLDDFIGP SQECIKPVKV EKRAGSGVAK IRIEDDGSYF QINQDGGTRR LEKAKVSLND CLACSGCITS AETVLITQQS HEELKKVLDA NKMAAPSQQR LVVVSVSPQS RASLAARFQL NPTDTARKLT SFFKKIGVHF VFDTAFSRHF SLLESQREFV RRFRGQADCR QALPLLASAC PGWICYAEKT HGSFILPHIS TARSPQQVMG SLVKDFFAQQ QHLTPDKIYH VTVMPCYDKK LEASRPDFFN QEHQTRDVDC VLTTGEVFRL LEEEGVSLPD LEPAPLDSLC SGASAEEPTS HRGGGSGGYL EHVFRHAARE LFGIHVAEVT YKPLRNKDFQ EVTLEKEGQV LLHFAMAYGF RNIQNLVQRL KRGRCPYHYV EVMACPSGCL NGGGQLQAPD RPSRELLQHV ERLYGMVRAE APEDAPGVQE LYTHWLQGTD SECAGRLLHT QYHAVEKAST GLGIRW
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分子量
53.0 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
NARFL (Nuclear Assembly Factor for Ribosomal Large subunit) is a protein that plays a crucial role in ribosome biogenesis and cellular growth regulation. Its significance has garnered attention due to its involvement in various cellular functions, including the assembly of ribosomal subunits and the maintenance of genomic integrity. Research into NARFL has revealed its potential links to human diseases, particularly cancers, where dysregulation of ribosome production can contribute to uncontrolled cell proliferation. The understanding of NARFL's structure and function is essential for elucidating its role in the cellular machinery. Recent advances in recombinant protein technology have enabled researchers to produce NARFL in the laboratory, facilitating detailed studies of its biochemical properties and interactions with other cellular components. By employing techniques such as X-ray crystallography and cryo-electron microscopy, scientists aim to uncover the molecular mechanisms by which NARFL influences ribosome assembly and function. This research not only enhances our understanding of fundamental biological processes but also holds the potential for therapeutic advancements in targeting diseases associated with ribosome dysfunction. Thus, the study of recombinant NARFL is a vital area of inquiry that bridges basic biology and medical research, promising insights into both fundamental cellular mechanisms and innovative treatment strategies.
