Analytical Data
-
基因名
RPS6Ka5
- Application
-
别名
RPS6Ka5；NFKB3；Transcription factor p65
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q04206
-
表达区间
1-551aa
-
氨基酸序列
MDELFPLIFPAEPAQASGPYVEIIEQPKQRGMRFRYKCEGRSAGSIPGERSTDTTKTHPTIKINGYTGPGTVRISLVTKDPPHRPHPHELVGKDCRDGFYEAELCPDRCIHSFQNLGIQCVKKRDLEQAISQRIQTNNNPFQVPIEEQRGDYDLNAVRLCFQVTVRDPSGRPLRLPPVLSHPIFDNRAPNTAELKICRVNRNSGSCLGGDEIFLLCDKVQKEDIEVYFTGPGWEARGSFSQADVHRQVAIVFRTPPYADPSLQAPVRVSMQLRRPSDRELSEPMEFQYLPDTDDRHRIEEKRKRTYETFKSIMKKSPFSGPTDPRPPPRRIAVPSRSSASVPKPAPQPYPFTSSLSTINYDEFPTMVFPSGQISQASALAPAPPQVLPQAPAPAPAPAMVSALAQAPAPVPVLAPGPPQAVAPPAPKPTQAGEGTLSEALLQLQFDDEDLGALLGNSTDPAVFTDLASVDNSEFQQLLNQGIPVAPHTTEPMLMEYPEAITRLVTGAQRPPDPAPAPLGAPGLPNGLLSGDEDFSSIADMDFSALLSQISS
-
分子量
60.2 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
RPS6KA5, also known as ribosomal protein S6 kinase A5, is a member of the S6 kinase family and plays a crucial role in various cellular processes, including cell growth, proliferation, and metabolism, by modulating key signaling pathways such as the mTOR pathway. Its dysregulation has been implicated in numerous diseases, particularly cancer, where it can contribute to tumor progression and resistance to therapies. Given its important role in signaling networks, RPS6KA5 has attracted significant attention as a potential therapeutic target. Recent studies have focused on understanding its molecular mechanisms, regulatory pathways, and its interactions with other proteins, paving the way for developing novel interventions. Additionally, the recombinant expression of RPS6KA5 has enabled researchers to investigate its structure and function in detail, facilitating the identification of small molecule inhibitors and the exploration of its role in tumor biology. The increasing interest in personalized medicine and targeted therapies further underscores the relevance of RPS6KA5 research, as elucidating its function could lead to improved treatment strategies for cancer and other diseases associated with its dysregulation.
