Analytical Data
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基因名
MRP63
- Application
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别名
MRP63；MRP63；Large ribosomal subunit Protein mL63
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BQC6
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表达区间
1-102aa
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氨基酸序列
MFLTALLWRG RIPGRQWIGK HRRPRFVSLR AKQNMIRRLE IEAENHYWLS MPYMTREQER GHAAVRRREA FEAIKAAATS KFPPHRFIAD QLDHLNVTKK WS
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分子量
12.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
MRP63, also known as the mitochondrial ribosomal protein of the large subunit 63, plays a critical role in mitochondrial function and protein synthesis within mammalian cells. As a component of the mitochondrial ribosome, MRP63 is essential for the translation of mitochondrially encoded proteins, which are crucial for oxidative phosphorylation and energy production. Dysregulation or mutations in MRP63 have been associated with various mitochondrial diseases, highlighting its importance in cellular metabolism and health. The study of MRP63 and its recombinant protein offers insights into the structure and function of mitochondrial ribosomes, enabling researchers to explore mechanisms of mitochondrial dysfunction and potential therapeutic interventions. Recent advancements in recombinant protein technology have facilitated the production and characterization of MRP63, providing opportunities to investigate its biochemical properties, interactions with other mitochondrial components, and its role in disease pathology. Understanding MRP63’s function at the molecular level is vital for developing strategies to address the challenges posed by mitochondrial-related disorders, thereby contributing to the broader field of mitochondrial biology and medicine.
