Analytical Data
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基因名
ADAMTSL4
- Application
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别名
TSRC1; PP1396; UNQ2803/PRO34012ADAMTS-like Protein 4
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6UY14
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表达区间
1-424aa
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氨基酸序列
MPAPPHPRTPLGSPAAYWKRVGHSACSASCGKGVWRPIFLCISRESGEELDERSCAAGARPPASPEPCHGTPCPPYWEAGEWTSCSRSCGPGTQHRQLQCRQEFGGGGSSVPPERCGHLPRPNITQSCQLRLCGHWEVGSPWSQCSVRCGRGQRSRQVRCVGNNGDEVSEQECASGPPQPPSREACDMGPCTTAWFHSDWSSKCSAECGTGIQRRSVVCLGSGAALGPGQGEAGAGTGQSCPTGSRPPDMRACSLGPCERTWRWYTGPWGECSSECGSGTQRRDIICVSKLGTEFNVTSPSNCSHLPRPPALQPCQGQACQDRWFSTPWSPCSRSCQGGTQTREVQCLSTNQTLSTRCPPQLRPSRKRPCNSQPCSQRPDDQCKDSSPHCPLVVQARLCVYPYYTATCCRSCAHVLERSPQDPS
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分子量
72.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ADAMTSL4 (A Disintegrin and Metalloproteinase with Thrombospondin Motifs 4) is a member of the ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin Motifs) family that plays a crucial role in various biological processes, including extracellular matrix remodeling and cell signaling. Its significance has been highlighted in studies related to connective tissue disorders and developmental processes. Research has shown that ADAMTSL4 may have implications in conditions such as osteoarthritis and certain cardiovascular diseases, where it potentially influences cell behavior and matrix composition. Furthermore, the regulation of ADAMTSL4 is of particular interest due to its association with the maintenance of tissue integrity and function. The development of recombinant ADAMTSL4 protein offers a valuable tool for studying its biological functions and therapeutic potential. By generating this recombinant protein, researchers can investigate its specific roles in the extracellular matrix and its interactions with other proteins, paving the way for new insights into its involvement in health and disease. Understanding the mechanisms by which ADAMTSL4 operates may lead to novel approaches in treating degenerative diseases and enhancing tissue regeneration. Consequently, the study of ADAMTSL4 not only advances knowledge in molecular biology but also holds promise for translational applications in regenerative medicine and pathology.
