Cat: PA1000-3265

Recombinant Human TP53I3 Protein,His

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Analytical Data

  • 基因名

    TP53I3

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    TP53I3;PIG3;Quinone oxidoreductase PIG3

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q53FA7

  • 表达区间

    1-332aa

  • 氨基酸序列

    MGSSHHHHHH SSGLVPRGSH MLAVHFDKPG GPENLYVKEV AKPSPGEGEV LLKVAASALN RADLMQRQGQ YDPPPGASNI LGLEASGHVA ELGPGCQGHW KIGDTAMALL PGGGQAQYVT VPEGLLMPIP EGLTLTQAAA IPEAWLTAFQ LLHLVGNVQA GDYVLIHAGL SGVGTAAIQL TRMAGAIPLV TAGSQKKLQM AEKLGAAAGF NYKKEDFSEA TLKFTKGAGV NLILDCIGGS YWEKNVNCLA LDGRWVLYGL MGGGDINGPL FSKLLFKRGS LITSLLRSRD NKYKQMLVNA FTEQILPHFS TEGPQRLLPV LDRIYPVTEI QEAHKYMEAN KNIGKIVLEL PQ

  • 分子量

    38 kD

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

TP53I3, also known as the Tumor Protein p53 Inducible Protein 3, is a gene that has garnered significant interest in cancer research due to its role in the cellular response to stress and its association with the tumor suppressor protein p53. The protein encoded by TP53I3 is involved in various biological processes, including apoptosis, cell cycle regulation, and the response to DNA damage, which positions it as a critical player in maintaining genomic integrity. Research has shown that TP53I3 is upregulated in response to p53 activation, suggesting its potential role as a mediator of the p53 pathway. Alterations in TP53I3 expression have been linked to various types of cancers, making it a candidate for further exploration in cancer diagnostics and therapeutics. Additionally, studies have suggested that TP53I3 may influence cellular metabolism and oxidative stress responses, contributing to tumor progression and therapies' efficacy. Given the pivotal role of p53 in cancer biology, understanding TP53I3's function and mechanism can provide insights into tumorigenesis and highlight its potential as a biomarker or therapeutic target in cancer management. Continued investigations into the TP53I3 protein could yield valuable information for developing novel strategies in cancer treatment, particularly in tumors exhibiting p53 dysfunction. The evolving research surrounding TP53I3 underscores its importance in the broader context of oncogenic processes and underscores the need for further studies to elucidate its precise role in cancer biology.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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