Analytical Data
-
基因名
UBE2R2
- Application
-
别名
UBE2R2；CDC34B；Ubiquitin-conjugating enzyme E2 R2
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q712K3
-
表达区间
2-238aa
-
氨基酸序列
AQQQMTSSQKALMLELKSLQEEPVEGFRITLVDESDLYNWEVAIFGPPNT LYEGGYFKAHIKFPIDYPYSPPTFRFLTKMWHPNIYENGDVCISILHPPV DDPQSGELPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMFRKW RDSKGKDKEYAEIIRKQVSATKAEAEKDGVKVPTTLAEYCIKTKVPSNDN SSDLLYDDLYDDDIDDEDEEEEDADCYDDDDSGNEES
-
分子量
32 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
UBE2R2, a member of the ubiquitin-conjugating enzyme family, plays a crucial role in the ubiquitination process, which is essential for protein degradation, cell cycle regulation, and various signaling pathways. The study of UBE2R2 has gained attention due to its implications in cancer biology and cellular stress responses. UBE2R2 is involved in the modification of target proteins with ubiquitin molecules, thereby influencing their stability and function. Abnormal expression or mutations in UBE2R2 have been associated with the development and progression of several malignancies, highlighting its potential as a therapeutic target. Recent research has focused on elucidating its structure, activity, and interaction with E3 ligases, as well as its regulatory mechanisms in cellular processes. Understanding the functional dynamics of UBE2R2 is vital for developing novel strategies to manipulate ubiquitin signaling pathways for therapeutic interventions in diseases characterized by aberrant protein homeostasis. As such, the characterization of UBE2R2 recombinant protein offers valuable insights into its biochemical properties and role in cellular mechanisms, paving the way for future studies aimed at targeting UBE2R2 in cancer treatment and other disorders linked to protein misregulation.
