Analytical Data
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基因名
PRKCDBP
- Application
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别名
Cavin 3; Cavin-3; CAVIN3; hSRBC; MGC20400; PRDBP_HUMAN; Prkcdbp; Protein kinase C delta binding protein; Protein kinase C delta-binding protein; Sdr related gene product that binds to c kinase; Serum deprivation response factor related gene product that binds to C kinase; Serum deprivation response factor-related gene product that binds to C-kinase; SRBC
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q969G5
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表达区间
1-261 aa
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氨基酸序列
MRESALERGP VPEAPAGGPV HAVTVVTLLE KLASMLETLR ERQGGLARRQ GGLAGSVRRI QSGLGALSRS HDTTSNTLAQ LLAKAERVSS HANAAQERAV RRAAQVQRLE ANHGLLVARG KLHVLLFKEE GEVPASAFQK APEPLGPADQ SELGPEQLEA EVGESSDEEP VESRAQRLRR TGLQKVQSLR RALSGRKGPA APPPTPVKPP RLGPGRSAEA QPEAQPALEP TLEPEPPQDT EEDPGRPGAA EEALLQMESV A
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分子量
27.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PRKCDBP (Protein Kinase C Delta Binding Protein) is a crucial adaptor protein that plays significant roles in various cellular processes, including signal transduction, cell survival, and apoptosis. Its interaction with Protein Kinase C (PKC) isoforms, particularly PKC delta, has garnered attention due to its implications in cancer progression, particularly in hematological malignancies. Research indicates that PRKCDBP may facilitate the localization and functional regulation of PKC delta, influencing downstream signaling pathways that promote tumorigenesis. Further investigation into the structural and functional characteristics of PRKCDBP can potentially unveil novel therapeutic targets in oncology, especially for cancers characterized by aberrant PKC signaling. As such, recombinant PRKCDBP proteins are being developed to elucidate its interactions and roles in cellular signaling networks, aiming to provide insights into its regulatory mechanisms and therapeutic potential. Understanding the dynamics of PRKCDBP in the context of cell signaling is vital, not only for cancer research but also for deciphering its involvement in other diseases where PKC signaling is disrupted. The study of this recombinant protein thus represents a promising frontier in the quest for targeted cancer therapies and improved clinical outcomes.
