Analytical Data
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Gene name
C18orf10
- Application
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Alternative Names
C18orf10; C18orf10 chromosome 18 open reading frame 10; Chromosome 18 open reading frame 10; DKFZP586M1523; HMFN0601; HsT3006; L17; PGs2; TPGS2_HUMAN; Tubulin polyglutamylase complex subunit 2
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q68CL5
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Expression Region
1-300aa
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AA Sequence
MEEEASSPGL GCSKPHLEKL TLGITRILES SPGVTEVTII EKPPAERHMI SSWEQKNNCV MPEDVKNFYL MTNGFHMTWS VKLDEHIIPL GSMAINSISK LTQLTQSSMY SLPNAPTLAD LEDDTHEASD DQPEKPHFDS RSVIFELDSC NGSGKVCLVY KSGKPALAED TEIWFLDRAL YWHFLTDTFT AYYRLLITHL GLPQWQYAFT SYGISPQAKQ WFSMYKPITY NTNLLTEETD SFVNKLDPSK VFKSKNKIVI PKKKGPVQPA GGQKGPSGPS GPSTSSTSKS SSGSGNPTRK
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Molecular Weight
59.7 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
C18orf10, also known as the "Chromosome 18 Open Reading Frame 10," is a protein that has garnered attention for its potential roles in various biological processes and diseases. Recent studies have suggested that C18orf10 may be involved in mitochondrial function, cellular metabolism, and possibly in the regulation of apoptosis. Given its association with mitochondrial activities, alterations in C18orf10 expression could have significant implications in cancer biology and metabolic disorders. Research has highlighted that the protein might interact with key cellular pathways and contribute to the pathophysiology of conditions such as neurodegenerative diseases and certain types of cancers. Additionally, the need for recombinant C18orf10 has emerged as scientists seek to elucidate its structure and functional mechanisms through in vitro and in vivo studies. Generating recombinant C18orf10 can facilitate biochemical assays, structural studies, and the exploration of its interactions at the molecular level. This understanding could pave the way for therapeutic interventions targeting related pathways, making C18orf10 a promising candidate for further exploration in translational medicine and biotherapeutic development. The urgency to study this protein emphasizes its potential as a biomarker or a therapeutic target, further necessitating the development of efficient expression systems for producing recombinant C18orf10 in sufficient quantities for comprehensive research.
