Analytical Data
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基因名
PTTG2
- Application
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别名
Pituitary tumor transforming 2; Pituitary tumor transforming gene 2 protein; Pituitary tumor-transforming gene 2 protein; PTTG2; PTTG2_HUMAN; Securin-2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NZH5
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表达区间
2-202 aa
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氨基酸序列
ATLIYVDKE IGEPGTRVAA KDVLKLESRP SIKALDGISQ VLTRRFGKTY DAPSALPKAT RKALGTVNRA TEKSVKTNGP RKQKQPSFSA KKMTEKTVKT KSSVPASDDA YPEIEKFFPF NLLDFESFDL PEERQIAHLP LSGVPLMILD EEGELEKLFQ LGPPSPVKMP SPPWECNLLQ SPSSILSTLD VELPAVCYDI DI
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分子量
22.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
PTTG2 (Pituitary Tumor-Transforming Gene 2) is a member of the PTTG family, which has been implicated in several critical biological processes, including cell cycle regulation, chromosome stability, and tumorigenesis. Its overexpression has been associated with various cancers, highlighting its potential as a biomarker and therapeutic target. The study of PTTG2 recombinant proteins has emerged as a significant focus in cancer research, as understanding its structure and function can provide insights into its role in oncogenesis. Researchers aim to characterize the protein's interactions with other cellular components, elucidating pathways that lead to tumor development. The production of recombinant PTTG2 allows for detailed functional studies, including assessing its impact on cell proliferation and apoptosis in cancer cells. Furthermore, investigating PTTG2’s role in chromosomal segregation can contribute to our knowledge of tumorigenic processes, as chromosomal instability is a hallmark of many malignancies. Overall, the exploration of PTTG2 recombinant protein stands at the intersection of molecular biology and cancer therapeutics, with the potential to pave the way for innovative diagnostic and treatment strategies.
