Analytical Data
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基因名
RAB41
- Application
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别名
OTTHUMP00000037883; OTTHUMP00000217399; RAB41; RAB41. member RAS homolog family; RAB41. member RAS oncogene family; RAB41_HUMAN; Ras-related protein Rab-41; RP13-26D14.4
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q5JT25
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表达区间
1-222 aa
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氨基酸序列
MSAFGHDEAW MEAGGFGLEA AERTEYQSLC KSKLLFLGEQ SVGKTSIISR FMYNSFGCAC QATVGIDFLS KTMYLEDQIV QLQLWDTAGQ ERFHSLIPSY IRDSTIAVVV YDITNINSFK ETDKWVEHVR AERGDDVVIM LLGNKIDLDN KRQVTAEQGE EKSRNLNVMF IETSAKTGYN VKKLFRRVAS ALLSTRTSPP PKEGTVEIEL ESFEESGNRS YC
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分子量
25.0 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
RAB41, a member of the RAB family of small GTPases, plays a crucial role in intracellular transport and membrane trafficking processes. As a key regulator of vesicle movement, RAB41 is involved in various cellular functions, including endocytosis and exocytosis, as well as the maintenance of cellular homeostasis. Recent studies have increasingly highlighted its significance in developmental biology and disease states, including cancer and neurodegenerative disorders, due to its involvement in the regulation of membrane-bound organelles. The recombinant expression of RAB41 protein provides an essential tool for the detailed investigation of its biochemical properties, functional interactions, and role in signaling pathways. By producing RAB41 in a controlled laboratory setting, researchers can analyze its GTPase activity, assess potential binding partners, and explore its regulatory mechanisms in cell signaling. Understanding the molecular mechanisms underlying RAB41 function may yield insights into its contribution to pathophysiological conditions and open avenues for therapeutic interventions. Moreover, the study of RAB41 and its related protein interactions can enhance our understanding of the broader RAB protein family and its implications in cellular communication and disease.
