Analytical Data
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基因名
ZNF638
- Application
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别名
ZNF638；NP220；ZFML；Zinc finger Protein 638
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q14966
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表达区间
1701-1978aa
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氨基酸序列
TFATLNTKGNEGDTVRDSIGFISSQVPEDPSTLVTVDEIQDDSSDLHLVTLDEVTEEDEDSLADFNNLKEELNFVTVDEVGEEEDGDNDLKVELAQSKNDHPTDKKGNRKKRAVDTKKTKLESLSQVGPVNENVMEEDLKTMIERHLTAKTPTKRVRIGKTLPSEKAVVTEPAKGEEAFQMSEVDEESGLKDSEPERKRKKTEDSSSGKSVASDVPEELDFLVPKAGFFCPICSLFYSGEKAMTNHCKSTRHKQNTEKFMAKQRKEKEQNEAEERSSR
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分子量
47.2 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
ZNF638, a member of the Krüppel-like family of zinc-finger proteins, has emerged as a significant player in various cellular processes such as transcriptional regulation, cell proliferation, and differentiation. Its potential roles in stem cell biology and cancer progression have attracted considerable research interest. Studies indicate that ZNF638 may influence gene expression by interacting with specific DNA sequences or partnering with other transcription factors, thus affecting the transcriptional landscape in cells. Furthermore, its dysregulation has been implicated in tumorigenesis, suggesting that ZNF638 could serve as a biomarker for certain cancers or a potential therapeutic target. The recombinant expression of ZNF638 enables researchers to explore its biochemical properties, functional interactions, and mechanistic pathways in vitro and in vivo. By producing and purifying ZNF638 as a recombinant protein, scientists can investigate its structure, binding affinities, and effects on gene expression, contributing to a better understanding of its biological significance and potential implications in medicine.
