Analytical Data
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Gene name
C21orf25
- Application
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Alternative Names
C2 domain-containing Protein 2. Transmembrane Protein 24-like
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Species
Human
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Source
E. coli
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Tag
GST-tag at N-terminal
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q9Y426
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Expression Region
1-388aa
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AA Sequence
MRLSPFHLQLEFHMKEKREDLQISWSFISVPEMAVNIQPKALGEDQVAETSAMSDVLKDILKHLAGSASPSVVLITKPTTVKEAQNLQCAASTAQESCPPKPPRAHELKLLVRNIHVLLLSEPGASGHINAVCVVQLNDPVQRFSSTLTKNTPDLMWEEEFTFELNAKSKELHLQISEAGRSSEGLLATATVPLDLFKKQPSGPQSFTLTSGSACGSSVLGSVTAEFSYMEPGELKSWPIPPPVPAAKIEKDRTVMPCGTVVTTVTAVKTKPRVDVGRASPLSSDSPVKTPIKVKVIEKDISVQAIACRSAPVSKTLSSSDTELLVLNGSDPVAEVAIRQLSESSKLKLKSPRKKSTIIISGISKVPSWWLGRCSSGHLSVTCCSSAL
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Molecular Weight
68.42 KDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
C21orf25, also known as chromosome 21 open reading frame 25, is a protein-coding gene located on human chromosome 21 that has garnered increasing interest due to its potential role in various biological processes and its association with Down syndrome, which is caused by an extra copy of chromosome 21. Research has indicated that C21orf25 may be involved in key cellular functions, including cell proliferation, differentiation, and apoptosis. Studies have suggested that alterations in the expression of C21orf25 could contribute to the phenotypic manifestations observed in individuals with Down syndrome, making it a candidate for further investigation in understanding the pathophysiology of this condition. Moreover, the protein's function and interactions remain largely unexplored, highlighting a critical gap in knowledge regarding its biological significance. Recombinant C21orf25 protein is being produced to facilitate in-depth studies, including its structural characterization, functional assays, and potential interactions with other cellular proteins. These investigations aim to elucidate the role of C21orf25 in cellular pathways and its implications in Down syndrome and related disorders, providing insights that could pave the way for novel therapeutic strategies. The development of this recombinant protein represents a promising step toward uncovering the underlying mechanisms of C21orf25 and its contribution to human health and disease.
