Analytical Data
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基因名
CCDC65
- Application
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别名
CCDC65; DRC2Dynein regulatory complex subunit 2; Coiled-coil domain-containing Protein 65; Testis development Protein NYD-SP28
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8IXS2
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表达区间
1-484aa
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氨基酸序列
MPKKEKMAKTPLSDEKQLLLFQQKLLAEEEMAKKKERLLSQFLKDKLAKEEHNSALNLNKINTQWRTVLREVKTRELHKDIEILSQTFERVVDCKDNVIKSLAKDLSEAEEQYAHALRSHLHNVDQLLALQRHRLSLLEESYNMELEALTKEFETERKTIIDQHEKEIHYLQDIFMAMEQNYIDSEYESKLEFQSMWNDLKNMNLEEKHFLRLHLENRVEDLWRKFQDVLKNYTDATEDRKAAFETLQVKDEKSSKEIEVQMKKIQKLQDAITISKGKIMIHSRESEDENRYIRNDKELVLVQLRKLKAQRTQARAASQKNLVRLTLESNATLKALRKIVDKGEKILKLAEICRKFETEEEKVLPFYSSVLTPKEQEGIQKNNLEELTEELTKVMVDYIGMENFWKRYNKVKLEQLSLQHRRAQLLDINGKLREMLKQYLDGISVSDEVLSQLNPLFIVNYQSNLLQPLSIRIAHPGDKQHPTT
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分子量
83.7 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CCDC65, known as Coiled-Coil Domain Containing 65, is a protein that has garnered attention in recent years due to its potential roles in various cellular processes and its implications in health and disease. Initially identified as a component in ciliary structures, CCDC65 is believed to be involved in the formation and maintenance of cilia, organelles critical for cellular signaling and movement. Disruptions in ciliary function have been linked to a range of disorders, collectively known as ciliopathies, which can affect organs and systems throughout the body. Furthermore, studies have indicated that CCDC65 may play a role in cellular signaling pathways, influencing processes such as cell migration, proliferation, and differentiation. The importance of CCDC65 in the context of disease, including its potential involvement in cancer and developmental disorders, has led to increased interest in its molecular mechanisms, structure, and interactions with other proteins. Thus, the characterization of CCDC65 as a recombinant protein is vital for elucidating its functional roles, facilitating drug development, and advancing our understanding of ciliary biology and associated pathologies. Researchers are actively exploring its biochemical properties and interactions, which could pave the way for novel therapeutic strategies targeting related diseases. The recombination and study of CCDC65 offer insights into fundamental biological processes and hold promise for future biotechnological applications.
