Analytical Data
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基因名
CDX1
- Application
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别名
Caudal type homeo box transcription factor 1 ; Caudal type homeobox 1; Caudal type homeobox Protein ; Caudal type homeobox Protein CDX1; Caudal type homeobox transcription factor 1; Caudal-type homeobox Protein 1; CDX1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P47902
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表达区间
1-265aa
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氨基酸序列
MYVGYVLDKD SPVYPGPARP ASLGLGPQAY GPPAPPPAPP QYPDFSSYSH VEPAPAPPTA WGAPFPAPKD DWAAAYGPGP AAPAASPASL AFGPPPDFSP VPAPPGPGPG LLAQPLGGPG TPSSPGAQRP TPYEWMRRSV AAGGGGGSGK TRTKDKYRVV YTDHQRLELE KEFHYSRYIT IRRKSELAAN LGLTERQVKI WFQNRRAKER KVNKKKQQQQ QPPQPPMAHD ITATPAGPSL GGLCPSNTSL LATSSPMPVK EEFLP
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分子量
139.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CDX1, or Caudal-related homeobox protein 1, is a crucial transcription factor that plays a significant role in the development and differentiation of the intestinal epithelium. Its expression is primarily observed in the gut, where it regulates genes essential for proper intestinal morphogenesis and function. Dysregulation of CDX1 has been linked to various gastrointestinal disorders, including colorectal cancer, highlighting its potential as a biomarker and therapeutic target. The study of CDX1 recombinant proteins has gained momentum as researchers aim to better understand its functional mechanisms and interactions at the molecular level. By producing CDX1 in a recombinant form, scientists can investigate its structural properties, binding affinities, and role in gene regulation using in vitro assays. This research not only enhances our understanding of CDX1's role in digestive health and disease but also opens avenues for developing novel treatments that can correct the pathways disrupted by its dysfunction. As ongoing studies continue to unveil the complexities of CDX1's interactions within cellular environments, the potential for leveraging its properties in clinical applications remains a compelling focus for future investigations.
