Analytical Data
-
Gene name
CHCHD6
- Application
-
Alternative Names
CHCHD6. CHCM1. MIC25
-
Species
Human
-
Source
E. coli
-
Tag
GST-tag at N-terminal
-
Purity
Greater than 90% as determined by SDS-PAGE.
-
Uniprot
Q9BRQ6
-
Expression Region
1-235aa
-
AA Sequence
MGSTESSEGRRVSFGVDEEERVRVLQGVRLSENVVNRMKEPSSPPPAPTSSTFGLQDGNLRAPHKESTLPRSGSSGGQQPSGMKEGVKRYEQEHAAIQDKLFQVAKREREAATKHSKASLPTGEGSISHEEQKSVRLARELESREAELRRRDTFYKEQLERIERKNAEMYKLSSEQFHEAASKMESTIKPRRVEPVCSGLQAQILHCYRDRPHEVLLCSDLVKAYQRCVSAAHKG
-
Molecular Weight
52.9 kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
CHCHD6, a member of the CHCHD (Coiled-Coil-Helix Domain Containing) family, has garnered significant attention in recent years due to its potential roles in mitochondrial function and cellular stress responses. This protein is characterized by the presence of coiled-coil and helix structures, which are crucial for its interaction with various molecular partners in the cell. Research indicates that CHCHD6 is involved in the regulation of apoptosis, oxidative stress, and mitochondrial dynamics, suggesting its importance in maintaining cellular homeostasis. Moreover, studies have linked CHCHD6 to several diseases, including neurodegenerative disorders, highlighting its role in pathways associated with cell survival and death. The recombinant expression of CHCHD6 allows for a deeper exploration of its structural and functional properties, facilitating the investigation of its interaction with other proteins and its implications in disease mechanisms. Understanding the biochemical characteristics and functional roles of CHCHD6 could pave the way for potential therapeutic strategies targeting mitochondrial dysfunction and related pathologies.
