Analytical Data
-
基因名
STX4A
- Application
-
别名
NY REN 31 antigen; p35 2; PLACENTAL; Renal carcinoma antigen NY REN 31; Renal carcinoma antigen NY-REN-31; Stx4; STX4_HUMAN; STX4A; Syntaxin 4; syntaxin 4A (placental); Syntaxin 4A; Syntaxin-4
-
种属
Human
-
表达系统
E. coli
-
标签
GST-tag at N-terminal
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q12846
-
表达区间
1-297 aa
-
氨基酸序列
MRDRTHELRQGDDSSDEEDKERVALVVHPGTARLGSPDEEFFHKVRTIRQTIVKLGNKVQELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKEEADENYNSVNTRMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSGQSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMINRIEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLLAVIIGVTVVG
-
分子量
60.6 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
STX4A, or Syntaxin 4A, is a member of the syntaxin family of proteins, which play crucial roles in the regulation of vesicular transport and membrane fusion processes in cells. This protein is particularly important in mediating the fusion of insulin-containing granules with the plasma membrane in pancreatic beta cells, thus influencing glucose homeostasis and insulin secretion. Research into STX4A has garnered significant interest due to its implications in metabolic disorders, including type 2 diabetes, whereby impaired insulin secretion contributes to hyperglycemia. Additionally, STX4A is involved in the exocytosis of various neurotransmitters and hormones, highlighting its pivotal role in neuroendocrine signaling. The molecular mechanisms governing STX4A function, including its interactions with other SNARE (Soluble N-ethylmaleimide-sensitive factor Attachment protein REceptor) proteins and regulatory factors, are critical for understanding its role in cellular communication. Moreover, alterations in STX4A expression or function have been associated with various pathologies, making it a potential therapeutic target. As a result, the study of STX4A recombinant protein has become an essential avenue of research, providing insights into its structure-function relationships and enabling the development of novel approaches to modulate its activity in disease states. By enriching our understanding of STX4A, researchers aim to harness its potential in improving metabolic health and addressing related diseases.
