Analytical Data
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基因名
TMTC4
- Application
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别名
TMTC4; Protein O-mannosyl-transferase TMTC4; EC 2.4.1.109; Transmembrane and TPR repeat-containing Protein 4
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q5T4D3
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表达区间
1-395 aa
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氨基酸序列
MLCKEQGITVLGLNAVFDILVIGKFNVLEIVQKVLHKDKSLENLGMLRNGGLLFRMTLLTSGGAGMLYVRWRIMGTGPPAFTEVDNPASFADSMLVRAVNYNYYYSLNAWLLLCPWWLCFDWSMGCIPLIKSISDWRVIALAALWFCLIGLICQALCSEDGHKRRILTLGLGFLVIPFLPASNLFFRVGFVVAERVLYLPSVGYCVLLTFGFGALSKHTKKKKLIAAVVLGILFINTLRCVLRSGEWRSEEQLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLVSAGCPVPVEGKMGYFSYL
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分子量
70.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TMTC4 (Transmembrane and Tetratricopeptide Repeats Containing 4) is a protein implicated in various cellular processes, and its research has gained traction due to its potential associations with neurological disorders and other diseases. As a member of the TMTC family, TMTC4 is believed to play a crucial role in the maintenance of cellular calcium homeostasis and the regulation of cellular signaling pathways. Recent studies suggest that alterations in TMTC4 expression or function may contribute to neurodegenerative conditions, highlighting its importance in neuronal health. Furthermore, the protein's tetratricopeptide repeats suggest a role in protein-protein interactions, which is essential for various biological functions, including apoptosis and oxidative stress responses. Understanding the molecular mechanisms by which TMTC4 exerts its effects can provide insights into its potential as a therapeutic target for the treatment of conditions related to calcium dysregulation and neuronal impairment. Overall, research on TMTC4 not only aims to elucidate its biological functions but also hopes to unravel its contributions to disease pathology, thereby paving the way for new clinical interventions and therapeutic strategies.
