Analytical Data
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基因名
REPIN1
- Application
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别名
REPIN1；RIP60；ZNF464；Replication initiator 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BWE0
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表达区间
1-567aa
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氨基酸序列
MLERRCRGPL AMGLAQPRLL SGPSQESPQT LGKESRGLRQ QGTSVAQSGA QAPGRAHRCA HCRRHFPGWV ALWLHTRRCQ ARLPLPCPEC GRRFRHAPFL ALHRQVHAAA TPDLGFACHL CGQSFRGWVA LVLHLRAHSA AKRPIACPKC ERRFWRRKQL RAHLRRCHPP APEARPFICG NCGRSFAQWD QLVAHKRVHV AEALEEAAAK ALGPRPRGRP AVTAPRPGGD AVDRPFQCAC CGKRFRHKPN LIAHRRVHTG ERPHQCPECG KRFTNKPYLT SHRRIHTGEK PYPCKECGRR FRHKPNLLSH SKIHKRSEGS AQAAPGPGSP QLPAGPQESA AEPTPAVPLK PAQEPPPGAP PEHPQDPIEA PPSLYSCDDC GRSFRLERFL RAHQRQHTGE RPFTCAECGK NFGKKTHLVA HSRVHSGERP FACEECGRRF SQGSHLAAHR RDHAPDRPFV CPDCGKAFRH KPYLAAHRRI HTGEKPYVCP DCGKAFSQKS NLVSHRRIHT GERPYACPDC DRSFSQKSNL ITHRKSHIRD GAFCCAICGQ TFDDEERLLA HQKKHDV
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
REPIN1, or recombination protein 1, has garnered significant attention in the field of molecular biology due to its crucial role in the DNA repair and recombination processes. This protein is essential for maintaining genomic stability, particularly in response to DNA double-strand breaks, which can occur due to environmental factors, replication errors, or cellular stress. Studies have shown that REPIN1 participates in homologous recombination and may influence the efficiency of DNA repair mechanisms. Understanding REPIN1's functions can provide insight into various biological processes, including development, aging, and the etiology of cancer. Since defects in DNA repair pathways are often linked to tumorigenesis, REPIN1 has emerged as a potential biomarker and therapeutic target in cancer treatment. Researchers are investigating the molecular mechanisms by which REPIN1 operates, including its interactions with other proteins involved in the DNA damage response. Additionally, advancements in recombinant protein technology have allowed for the production of REPIN1 in vitro, facilitating detailed structural and functional studies. Current research aims to elucidate the precise roles of REPIN1 in cellular processes and its potential implications in disease states, paving the way for innovative approaches in cancer therapy and genetic engineering.
