Analytical Data
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基因名
GBX1
- Application
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别名
GBX1Homeobox protein GBX-1; Gastrulation and brain-specific homeobox protein 1
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q14549
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表达区间
1-363aa
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氨基酸序列
MQRAGGGSAPGGNGGGGGGGPGTAFSIDSLIGPPPPRSGHLLYTGYPMFMPYRPLVLPQALAPAPLPAGLPPLAPLASFAGRLTNTFCAGLGQAVPSMVALTTALPSFAEPPDAFYGPQELAAAAAAAAATAARNNPEPGGRRPEGGLEADELLPAREKVAEPPPPPPPHFSETFPSLPAEGKVYSSDEEKLEASAGDPAGSEQEEEGSGGDSEDDGFLDSSAGGPGALLGPKPKLKGSLGTGAEEGAPVTAGVTAPGGKSRRRRTAFTSEQLLELEKEFHCKKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRIKAGNVSSRSGEPVRNPKIVVPIPVHVNRFAVRSQHQQMEQGARP
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分子量
66.33 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GBX1, or Gastrulation Brain Homeobox 1, is a transcription factor crucial for early embryonic development, particularly in the formation of the brain and axial structures. Research into GBX1 has gained prominence due to its significant role in regulating gene expression during developmental processes and its involvement in various pathological conditions. Alterations in GBX1 expression have been linked to neural tube defects and other neurodevelopmental disorders, highlighting its potential significance in understanding congenital malformations. Furthermore, GBX1 has been implicated in cancer biology, where it may contribute to the proliferation and differentiation of cancer cells. The recombinant protein form of GBX1 is of particular interest for experimental studies, as it allows researchers to investigate its molecular mechanisms and interactions in detail. By studying GBX1 in a controlled environment, scientists aim to elucidate its functional roles in both healthy and diseased states, which could pave the way for novel therapeutic strategies targeting GBX1-related pathways. Overall, the characterization of GBX1 recombinant protein holds promising implications for developmental biology and medical research, providing insights that could translate into clinical interventions for various diseases.
