Analytical Data
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Gene name
TADA3
- Application
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Alternative Names
ADA3 homolog ;hADA3STAF54Transcriptional adapter 3-like ;ADA3-like protein
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Species
Human
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Source
E. coli
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Tag
N- GST
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
O75528
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Expression Region
1-238aa
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Molecular Weight
53.9 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
TADA3, or TAT-mediated protein transactivation domain 3, is a crucial component of several transcriptional regulatory complexes involved in gene expression and cellular differentiation. It plays an essential role in processes such as embryonic development, immune responses, and the regulation of various biological pathways. The study of TADA3 has gained significant attention due to its impact on cancer biology, as dysregulation of transcription factors and coactivators contributes to tumorigenesis. Research has shown that TADA3 is essential for the activity of certain oncogenic transcription factors, thereby influencing cell proliferation and survival. Furthermore, TADA3 is a target for therapeutic strategies aimed at modulating gene expression in various diseases. Understanding the structural and functional dynamics of TADA3 can provide insights into its mechanisms of action and its interactions with other proteins within the transcriptional machinery. This knowledge is vital for developing novel treatments and interventions in cancer and other disorders related to transcriptional dysregulation. Consequently, TADA3 represents an important focal point for ongoing studies that aim to decipher its roles in health and disease, paving the way for potential biotechnological applications in gene therapy and precision medicine.
