Cat: IPD-X38909

Recombinant Human NAAA Protein,His

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Analytical Data

  • 基因名

    NAAA

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    ASAHL; PLT; N-Acylethanolamine-Hydrolyzing Acid Amidase; N-Acylsphingosine Amidohydrolase Like; Acid ceramidase-like protein

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    N-His

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q02083

  • 表达区间

    Asp112~Lys359

  • 分子量

    28kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

The study of the NAAA (N-acylethanolamine acid amidase) recombinant protein has garnered significant attention in recent years due to its potential implications in various physiological and pathological processes. NAAA is an important enzyme involved in the metabolism of bioactive lipids, specifically in the hydrolysis of N-acylethanolamines, which play crucial roles in modulating pain, inflammation, and neuroprotection. Dysregulation of NAAA activity has been associated with several health conditions, including neurodegenerative diseases, metabolic disorders, and pain syndromes. Recombinant production of NAAA allows for detailed characterization of its enzymatic properties, substrate specificity, and functional role in lipid metabolism. Furthermore, understanding the molecular mechanisms underlying NAAA's activity may lead to the development of novel therapeutic strategies targeting pain and inflammation. Advances in recombinant protein technology, such as the use of expression systems and purification methods, have facilitated the exploration of NAAA's structure-function relationships, paving the way for the design of inhibitors or modulators that could enhance its therapeutic potential. Consequently, research into NAAA recombinant protein not only contributes to our fundamental understanding of lipid signaling pathways but also holds promise for the development of innovative treatments for various diseases.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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