Analytical Data
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Gene name
NSMCE3
- Application
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Alternative Names
Hepatocellular carcinoma-associated protein 4 MAGE-G1 antigen Melanoma-associated antigen G1 Necdin-like protein 2
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Species
Human
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Source
E. coli
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Tag
N- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
Q96MG7
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Expression Region
1-304aa
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Molecular Weight
38.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
The NSMCE3 protein, part of the non-SMC (non-Sister Chromatid Maintenance) MAGE family, plays a crucial role in various cellular processes, including DNA repair, chromosomal stability, and the regulation of the cell cycle. Its involvement in the maintenance of genomic integrity has garnered attention, particularly in the context of cancer research, where mutations or dysregulation of these proteins can lead to increased tumorigenesis. Recent studies indicate that NSMCE3 may act as a tumor suppressor, suggesting that its proper function is essential for preventing uncontrolled cell growth. The significance of NSMCE3 in the cellular response to DNA damage and its interactions with other key proteins in the DNA repair pathways have made it a subject of extensive investigation. Researchers are focusing on the biochemical properties of NSMCE3, including its structural features and the mechanisms by which it exerts its functions, to better understand how its dysfunction could contribute to cancer progression. Additionally, the development of NSMCE3 recombinant proteins for experimental purposes aims to elucidate its role in cellular mechanisms and potentially identify therapeutic targets for cancer treatment. Overall, the study of NSMCE3 and its recombinant forms holds promise for advancing our knowledge of cancer biology and enhancing our ability to develop effective therapies.
