Analytical Data
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基因名
HOMER2
- Application
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别名
(Homer-2)(Cupidin)
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种属
Human
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表达系统
E. coli
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标签
N- His & C- Myc
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NSB8
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表达区间
1-354aa
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分子量
48.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
HOMER2 is a member of the Homer family of proteins, which are crucial for synaptic signaling and the organization of neuronal networks. As an essential scaffolding protein, HOMER2 interacts with various receptors, including metabotropic glutamate receptors (mGluRs) and inositol trisphosphate receptors (IP3Rs), playing a pivotal role in signal transduction pathways involved in synaptic plasticity and neurodevelopment. Research has indicated that HOMER2 is implicated in various neurological conditions, including schizophrenia, autism, and substance abuse disorders, highlighting its importance in maintaining synaptic integrity and function. The study of HOMER2 recombinant proteins provides valuable insights into its structure-function relationships, enabling researchers to dissect its specific interactions and regulatory mechanisms. Advances in recombinant protein technology have made it possible to produce HOMER2 in sufficient quantities for biochemical assays and structural analyses. Understanding the precise role of HOMER2 in neuronal signaling not only contributes to basic neuroscience but also has potential therapeutic implications for targeted treatments in synaptopathies and related disorders. As investigations into HOMER2 continue to evolve, the knowledge gained from these studies may pave the way for innovative strategies aimed at modulating synaptic functions in various brain disorders.
