Analytical Data
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基因名
REXO1
- Application
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别名
REXO1;ELOABP1;KIAA1138;TCEB3BP1;RNA exonuclease 1 homolog
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8N1G1
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表达区间
1060-1221aa
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氨基酸序列
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSIYAL DCEMSYTTYG LELTRVTVVD TDVHVVYDTF VKPDNEIVDY NTRFSGVTEA DLADTSVTLR DVQAVLLSMF SADTILIGHS LESDLLALKV IHSTVVDTSV LFPHRLGLPY KRSLRNLMAD YLRQIIQDNV DGHSSSEDAG ACMHLVIWKV REDAKTKR
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分子量
22 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
REXO1, also known as RNA exonuclease 1, is a member of the 3' to 5' exoribonuclease family and plays a crucial role in RNA metabolism, including mRNA decay and processing. Its involvement in various cellular processes, such as the regulation of gene expression and the maintenance of RNA quality control, has made REXO1 a focal point of research in molecular biology. Recent studies have indicated that REXO1 may also be linked to important biological processes, such as responses to stress and the regulation of cellular proliferation. Abnormal REXO1 expression has been implicated in a variety of diseases, including cancers, where it may influence tumor progression and response to therapy. The production of recombinant REXO1 protein has become essential for investigating its biochemical properties, enzymatic activity, and structural characteristics. Such studies can provide insights into the mechanisms by which REXO1 contributes to RNA metabolism and its potential therapeutic implications. Understanding REXO1's function at the molecular level may offer novel avenues for targeting RNA-related dysregulation in diseases, highlighting the importance of recombinant protein studies in elucidating its role in cellular physiology and pathophysiology. Consequently, research on REXO1 not only enhances our comprehension of fundamental biology but also paves the way for potential biomedical applications.












