Cat: PA1000-2725

Recombinant Human RHOQ Protein,His

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Analytical Data

  • 基因名

    RHOQ

  • Application

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    RHOQ;ARHQ;RASL7A;TC10;Rho-related GTP-binding Protein RhoQ

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    P17081

  • 表达区间

    1-202aa

  • 氨基酸序列

    MAHGPGALML KCVVVGDGAV GKTCLLMSYA NDAFPEEYVP TVFDHYAVSV TVGGKQYLLG LYDTAGQEDY DRLRPLSYPM TDVFLICFSV VNPASFQNVK EEWVPELKEY APNVPFLLIG TQIDLRDDPK TLARLNDMKE KPICVEQGQK LAKEIGACCY VECSALTQKG LKTVFDEAII AILTPKKHTV KKRIGSRCIN CC

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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Protein Description

RHOQ, a member of the Rho GTPase family, plays a crucial role in various cellular processes, including cytoskeletal dynamics, cell migration, and intracellular signaling. Research into RHOQ has gained momentum due to its potential implications in cancer progression and other diseases characterized by aberrant cell behavior. The protein functions as a molecular switch, cycling between an active GTP-bound state and an inactive GDP-bound form, which regulates its interaction with downstream effectors. Investigating RHOQ's signaling pathways and its regulatory mechanisms can provide insights into its role in pathological conditions. The study of recombinant RHOQ proteins is particularly significant because it allows for detailed biochemical and structural analyses, facilitating the understanding of its function and interactions at a molecular level. Researchers employ various methods, such as X-ray crystallography and NMR spectroscopy, to study these proteins, while techniques like pull-down assays and cell-based assays are used to explore their interactions with other cellular components. The exploration of RHOQ's biological functions and its potential as a therapeutic target presents a promising area of study, as modulating its activity could lead to novel strategies for managing diseases driven by dysregulated Rho GTPases. Overall, the research on RHOQ recombinant proteins is pivotal for elucidating the complex network of signaling pathways in which it is involved and providing insights into the molecular underpinnings of various diseases.

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IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
IPODIX North America (HQ)
Proteintech Group, Inc
5500 Pearl Street, Suite 400
Rosemont, IL 60018, USA
1-888-478-4522
proteintech@ptglab.com
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