Analytical Data
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基因名
ARRDC2
- Application
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别名
ARRDC2; PP2703; Arrestin domain-containing Protein 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8TBH0
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表达区间
1-407aa
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氨基酸序列
MLFDKVKAFS VQLDGATAGV EPVFSGGQAV AGRVLLELSS AARVGALRLR ARGRAHVHWT ESRSAGSSTA YTQSYSERVE VVSHRATLLA PDTGETTTLP PGRHEFLFSF QLPPTLVTSF EGKHGSVRYC IKATLHRPWV PARRARKVFT VIEPVDINTP ALLAPQAGAR EKVARSWYCN RGLVSLSAKI DRKGYTPGEV IPVFAEIDNG STRPVLPRAA VVQTQTFMAR GARKQKRAVV ASLAGEPVGP GQRALWQGRA LRIPPVGPSI LHCRVLHVDY ALKVCVDIPG TSKLLLELPL VIGTIPLHPF GSRSSSVGSH ASFLLDWRLG ALPERPEAPP EYSEVVADTE EAALGQSPFP LPQDPDMSLE GPFFAYIQEF RYRPPPLYSE EDPNPLLGDM RPRCMTC
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分子量
44.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
The research on ARRDC2, an arrestin domain-containing protein, has gained significant attention due to its role in various cellular processes, including receptor signaling, endocytosis, and apoptosis. ARRDC2 is a member of a larger family of arrestin proteins, which are known to modulate the activity of G protein-coupled receptors (GPCRs) and participate in the regulation of intracellular signaling pathways. Studies have shown that ARRDC2 interacts with various membrane proteins and is involved in the sorting and trafficking of these proteins within cells. Furthermore, its dysregulation has been associated with several diseases, including cancer, highlighting its potential as a therapeutic target. The recombinant expression of ARRDC2 allows for detailed structural and functional studies, enabling researchers to elucidate its specific interactions and mechanisms of action. By characterizing ARRDC2 in vitro, scientists aim to uncover its contributions to cellular homeostasis and to explore its potential implications in health and disease, paving the way for novel therapeutic strategies. Understanding the biological significance of ARRDC2 could enhance our insight into the complex networks that regulate cell signaling and adaptation, making it a valuable focus for future biomedical research.
