Analytical Data
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基因名
CXCL16
- Application
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别名
CXCL16;SCYB16;C-X-C motif chemokine 16
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种属
Mouse
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8BSU2
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表达区间
27-114aa
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氨基酸序列
NQGSVAGSCS CDRTISSGTQ IPQGTLDHIR KYLKAFHRCP FFIRFQLQSK SVCGGSQDQW VRELVDCFER KECGTGHGKS FHHQKHLP
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分子量
28 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CXCL16, a chemokine belonging to the CXC family of chemokines, plays a significant role in the immune response and inflammation. It is primarily expressed by various cell types, including dendritic cells, macrophages, and endothelial cells, and is involved in the recruitment of immune cells, particularly T cells and dendritic cells, to sites of inflammation and infection. The protein exerts its biological effects through binding to its receptor, CXCR6, which is expressed on several immune cell types, thereby facilitating immune surveillance and modulating the adaptive immunity. Given its crucial functions, CXCL16 has been associated with various pathological conditions, including cancer, autoimmune diseases, and chronic inflammatory disorders. Thus, generating recombinant CXCL16 protein has become essential for studying its functional roles in these contexts. Researchers aim to produce high-purity recombinant CXCL16 to explore its chemotactic properties, receptor interactions, and potential therapeutic applications, such as targeted immunotherapy and vaccine development. Understanding the precise mechanisms by which CXCL16 influences immune responses may provide insights into developing novel treatments for diseases characterized by immune dysregulation. This protein's study can deepen our understanding of immune cell trafficking and has significant implications for devising strategies to enhance anti-tumor immunity or attenuate harmful inflammation in autoimmune conditions.












