Analytical Data
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Gene name
ANP32A / PHAP1
- Application
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Alternative Names
ANP32A / PHAP1；
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Species
Human
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P39687
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Expression Region
1-249aa
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AA Sequence
MGSSHHHHHHSSGLVPRGSHMEMGRRIHLELRNRTPSDVKELVLDNSRSN EGKLEGLTDEFEELEFLSTINVGLTSIANLPKLNKLKKLELSDNRVSGGL EVLAEKCPNLTHLNLSGNKIKDLSTIEPLKKLENLKSLDLFNCEVTNLND YRENVFKLLPQLTYLDGYDRDDKEAPDSDAEGYVEGLDDEEEDEDEEEYD EDAQVVEDEEDEDEEEEGEEEDVSGEEEEDEEGYNDGEVDDEEDEEELGE EERGQKRKREPEDEGEDDD
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Molecular Weight
31 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
ANP32A, also known as PHAP1 (PH domain and Leucine-rich repeat protein 1), is a member of the ANP32 family involved in various cellular processes, including transcription regulation, apoptosis, and the modulation of protein phosphatase 2A (PP2A) activity. Research into ANP32A/PHAP1 has gained considerable attention due to its implications in cell signaling pathways and potential roles in diseases such as cancer and neurodegenerative disorders. Understanding the structure and function of this protein is critical, as it can influence the stability of many cellular proteins and impact overall cellular homeostasis. Recombinant ANP32A/PHAP1 proteins are essential for elucidating their biochemical properties, interaction networks, and mechanisms of action at the molecular level. Advances in recombinant DNA technology have enabled the production of these proteins in sufficient quantities for in vitro studies, facilitating the exploration of their roles in cellular processes. The ability to study ANP32A/PHAP1 in detail may uncover novel therapeutic targets and strategies for diseases where this protein plays a critical role. Thus, ongoing research focuses on optimizing recombinant protein production, characterizing its functional domains, and uncovering its regulatory mechanisms in different biological contexts.
