Analytical Data
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基因名
SCGB1A1
- Application
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别名
SCGB1A1;KIAA1174;LIMR;Protein LMBR1L
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P11684
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表达区间
20-91aa
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氨基酸序列
MKHHHHHHAS EICPSFQRVI ETLLMDTPSS YEAAMELFSP DQDMREAGAQ LKKLVDTLPQ KPRESIIKLM EKIAQSSLCN
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分子量
9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SCGB1A1, also known as Secretoglobin family 1A member 1 or Clara cell protein (CC10), is a secreted glycoprotein primarily expressed in the epithelial cells of the lung and involved in various biological functions, including anti-inflammatory responses and surfactant metabolism. Research into SCGB1A1 is significant due to its potential role in respiratory diseases such as asthma, chronic obstructive pulmonary disease (COPD), and pulmonary fibrosis. Abnormal expression levels of SCGB1A1 have been linked to airway inflammation and remodeling, making it a candidate for understanding the molecular mechanisms of these conditions. Additionally, SCGB1A1 has been studied for its potential as a biomarker for lung disease and its implications in lung cancer pathogenesis. The generation of recombinant SCGB1A1 proteins allows for detailed characterization of its structure and function, paving the way for new therapeutic strategies. By employing techniques such as protein expression systems and purification methods, researchers can obtain sufficient quantities of this protein for in-depth study, which enhances our understanding of its biological roles and its potential applications in clinical settings. Overall, the exploration of SCGB1A1 as a recombinant protein is essential for advancing our knowledge of pulmonary biology and developing targeted therapies for respiratory ailments.












