Analytical Data
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基因名
C19orf51
- Application
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别名
Dynein axonemal assembly factor 3
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8N9W5
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表达区间
1-541aa
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氨基酸序列
MTTPAGSGSGFGSVSWWGLSPALDLQAESPPVDPDSQADTVHSNPELDVLLLGSVDGRHLLRTLSRAKFWPRRRFNFFVLENNLEAVARHMLIFSLALEEPEKMGLQERSETFLEVWGNALLRPPVAAFVRAQADLLAHLVPEPDRLEEQLPWLSLRALKFRERDALEAVFRFWAGGEKGPQAFPMSRLWDSRLRHYLGSRYDARRGVSDWDLRMKLHDRGAQVIHPQEFRRWRDTGVAFELRDSSAYHVPNRTLASGRLLSYRGERVAARGYWGDIATGPFVAFGIEADDESLLRTSNGQPVKTAGEITQHNVTELLRDVAAWGRARATGGDLEEQQHAEGSPEPGTPAAPTPESFTVHFLPLNSAQTLHHKSCYNGRFQLLYVACGMVHLLIPELGACVAPGGNLIVELARYLVDVRQEQLQGFNTRVRELAQAAGFAPQTGARPSETFARFCKSQESALGNTVPAVEPGTPPLDILAQPLEASNPALEGLTQPLQGGTPHCEPCQLPSESPGSLSEVLAQPQGALAPPNCESDSKTGV
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分子量
85.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
C19orf51, also known as the interferon-induced protein 44-like (IFI44L), has garnered significant attention in recent years due to its potential role in immune response and viral infections. Positioned on chromosome 19, this gene encodes a protein that is implicated in the regulation of immune signaling pathways, particularly those involving interferons, which are crucial for the host defense against pathogens. Research has shown that C19orf51 may play a role in modulating the activity of immune cells and influencing inflammation, making it a candidate for studies related to autoimmune diseases and infectious agents. Additionally, its involvement in the cellular response to stress and viral challenges underscores its importance in understanding the mechanisms of host-pathogen interactions. Advances in recombinant protein technology have enabled researchers to produce C19orf51 in heterologous systems, facilitating in vitro studies of its structure and function. This recombinant protein can be utilized in various assays to explore its interactions with other proteins and its downstream effects on immune responses. As scientists continue to elucidate the biological functions of C19orf51, the insights gained could pave the way for novel therapeutic approaches targeting immune modulation in diseases where the protein is dysregulated. The ongoing investigation into the role of C19orf51 in viral infections, particularly in the context of emerging pathogens, highlights its relevance in contemporary biomedical research and its potential implications for public health strategies.
