Analytical Data
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基因名
GLU-1D-1D
- Application
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别名
GLU-1D-1D；GLUR5；Glutamate receptor ionotropic. kainate 1
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种属
E.coli
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P10388
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表达区间
22-194aa
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氨基酸序列
EGEASEQLQCERELQELQERELKACQQVMDQQLRDISPECHPVVVSPVAGQYEQQIVVPPKGGSFYPGETTPPQQLQQRIFWGIPALLKRYYPSVTCPQQVSYYPGQASPQRPGQGQQPGQGQQGYYPTSPQQPGQWQQPEQGQPRYYPTSPQQSGQLQQPAQGQQPGQGQQG
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分子量
20.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
GLU-1D-1D recombinant protein has emerged as a focal point in the study of carbohydrate metabolism and its associated disorders. As one of the key members of the glutamate transporter family, GLU-1D-1D plays a vital role in the regulation of glutamate levels in the synaptic cleft, thereby influencing neurotransmission and neuronal excitability. Recent research has highlighted its importance in neurodegenerative diseases, such as Alzheimer's and Parkinson's, where impaired glutamate clearance may contribute to excitotoxicity and neuronal death. The characterization of GLU-1D-1D recombinant protein enables scientists to delve deeper into its structure-function relationships and its potential interactions with various ligands and inhibitors. Furthermore, recombinant production allows for the generation of large quantities of purified protein for biochemical assays and structural analysis, thereby facilitating the development of therapeutic strategies aimed at restoring normal glutamate homeostasis. As we continue to unravel the complexities of GLU-1D-1D’s function, its study not only enhances our understanding of neurobiology but also paves the way for innovative approaches in treating related pathologies. Overall, the research surrounding GLU-1D-1D recombinant protein underscores its significance in both basic and applied sciences, reflecting the growing recognition of the critical role of glutamate transporters in brain health.
