Analytical Data
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基因名
C9orf37
- Application
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别名
ARRDC1-AS1; C9orf37; AD038Uncharacterized Protein ARRDC1-AS1; ARRDC1 antisense RNA 1; ARRDC1 antisense gene Protein 1
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9H2J1
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表达区间
1-176aa
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氨基酸序列
MEFHYVAQADLELLTSSNPPASASQSTGITGGSHRARPGPVHFIDKVTDKPSHSHPFALKENWNLNPEPSSPPSPLFLEAPSRQASQHHGASPGAGTSAGCPFEKCCSTEPCLSGLGDVGRGEAASLRARPGSGASRGQGPGSRVSCRRDLGKPLHAPAGFSAGEVHTTPLGNLGA
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分子量
44.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
C9orf37 is a gene located on chromosome 9 that has garnered significant interest due to its potential association with various neurodegenerative diseases, particularly frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). Recent genomic studies have identified mutations in this gene, linking them to both familial and sporadic cases of these disorders. Understanding the protein encoded by C9orf37 is crucial, as it may play a role in cellular functions that contribute to neurodegenerative pathology. The research surrounding the recombinant C9orf37 protein focuses on elucidating its structural and functional characteristics, which might shed light on its biological role and involvement in neurodegenerative processes. Experimental studies aim to produce high-quality recombinant C9orf37 protein for in vitro analyses, allowing scientists to investigate its interactions with other cellular components and its impact on neuronal health. By examining the protein's properties, researchers hope to uncover mechanisms that lead to neurodegeneration and identify potential therapeutic targets. The study of C9orf37 not only enhances our understanding of its specific functions but also contributes to the broader field of neurobiology, offering insights into the molecular underpinnings of diseases that significantly impact the aging population.
