Analytical Data
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Gene name
Mcpt1
- Application
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Alternative Names
Mcpt1；CYH；CYM；Chymase
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Species
Mouse
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Source
E. coli
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Tag
His tag N-Terminus
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
P11034
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Expression Region
21-246aa
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AA Sequence
IIGGVEARPH SRPYMAHLKI ITDRGSEDRC GGFLIAPQFV LTAAHCKGRE ITVTLGAHDV SKSESTQQRI KVEKQIIHKN YNVSFNLYDI MLLKLEEKAE LTPTVDVIPL PGPSDFIDPG KMCWTAGWGK TGEKEPTSET LREVELRIMD KEACKMYKHY DYNFQVCVGS STKLKTAYMG DSGGPLLCAG VAHGIVSYGD SHGKPPAVFT RISAYVPWIK TVINGK
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Molecular Weight
27.0 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
Mcpt1, or Mast Cell Protease 1, is a serine protease predominantly expressed in mast cells, playing a crucial role in the immune response and inflammation. The study of Mcpt1 has gained attention due to its involvement in various physiological and pathological processes, including allergic reactions, asthma, and tissue remodeling. Research has demonstrated that Mcpt1 participates in the regulation of pro-inflammatory cytokines and helps modulate the activity of immune cells. Additionally, elevated levels of this protease have been associated with chronic inflammatory diseases, making it a potential biomarker for disease progression. Moreover, the recombinant production of Mcpt1 provides opportunities for further investigation into its enzymatic functions and therapeutic applications. With advances in recombinant protein technology, researchers are now able to produce large quantities of Mcpt1 for structural studies, functional assays, and the development of targeted treatments. Understanding the precise role of Mcpt1 in immune responses could lead to novel strategies for mitigating inflammation and treating related disorders, highlighting its significance in both basic research and clinical applications.
