Analytical Data
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基因名
CCDC148
- Application
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别名
CCDC148Coiled-coil domain-containing Protein 148
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8NFR7
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表达区间
1-591aa
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氨基酸序列
MCAASASPDN LVFHMKNEMR NIKYKPVDYQ QLRALTEAKK LASASAKLKI RKAMLTSKLS KEQTLIKQHK QVWWQEYQRL NEVRCKMESE IKSLLNEENI GNECLCDLTN FEQELSEQQC TYLKNVINPI QQLRADLKYR QHHTLQHSHP HIEFNSMKVL EEVDFVKKQL KTVFERLRLE QQRIENDLSD WSIKILDHSL EEKTNPLSEL PIELESLECP YPDLKSSILS EFYKFTQKYQ KKLQDFNLQL EDIYRNCQLS EEDHWIYQAI LDQYPGDLFG RRTLYLDMLQ RYFPHKSRHD LVEHEKYCDQ YRFAIEQQNI LISNWNKNKK DFIQKAVLTL TEACATHEME SMLAKDKKKQ QELCADLKAK VRQWRAHQEE VARLEMEISA RRREKEEEKE KLWKKKELLQ RAEKKKKIKK YWAKKKQKWQ EMEMRDLQRL EELKKLIAEQ SLKDRERVKY RQELLERRLM EKKEVALQEA HEDKERARRL EALRKQVAVV AQFDPVRMMS DTMASKARMG IEIEEEFILQ KPLFTLNTYN EQQIISDPRL RFELALREAG LHRTLYAKEI LPKISPQKPP RKDMESTVFK I
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分子量
71.0 KDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CCDC148 (Coevolved Coiled-Coil Domain) is a protein of significant interest due to its involvement in critical cellular processes, including cell division and cytoskeletal organization. Recent studies have highlighted its potential role in mitotic spindle assembly and function, as well as in maintaining genomic stability. Abnormalities in the expression or function of CCDC148 may be linked to various diseases, including cancer, making it a target for therapeutic interventions. The recombinant expression of CCDC148 allows for detailed biochemical characterization and functional assays, contributing to our understanding of its mechanistic roles within the cell. By utilizing advanced techniques in molecular biology, researchers can investigate the structure-function relationships of this protein, providing insights that are essential for unraveling its biological significance. The generation and study of CCDC148 recombinant proteins also pave the way for developing novel biomarkers for disease diagnosis and potential targets for drug development, thus enhancing our overall understanding of cellular dynamics and disease pathogenesis. As research progresses, elucidating the precise roles of CCDC148 in different cellular contexts will be paramount for advancing therapeutic strategies aimed at diseases associated with its dysregulation.
