Analytical Data
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基因名
CCDC37
- Application
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别名
CFAP100; CCDC37Cilia- and flagella-associated Protein 100; Coiled-coil domain-containing Protein 37
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q494V2
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表达区间
1-611aa
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氨基酸序列
MSEIPSTIVSKNMTNDKNSLESMNISSSSSTEENPKKQARKNEEHGPDPSANPFHLSGDVDFFLLRDQERNKALSERQQQKTMRVHQKMTYSSKVSAKHTSLRRQLQLEDKQEDLEARAEAEHQRAFRDYTTWKLTLTKEKNVEPENMSGYIKQKRQMFLLQYALDVKRREIQRLETLATKEEARLERAEKSLEKDAALFDEFVRENDCSSVQAMRAAEKETKAKIEKILEIRDLTTQIVNIKSEISRFEDTLKHYKVYKDFLYKLSPKEWLEEQEKKHSFLKKAKEVSEASKESSVNSTPGDKGPGIKGKASSMWAKEGQGTKKPWRFLQTMRLGRSPSYLSSPQQGSQPSESSGGDSRGSNSPIPPTQEDTDSDGEEPQLYFTEPQQLLDVFRELEEQNLSLIQNSQETEKTLEELSHTLKHTQIRMDREVNQLKQWVTTMMMSITKEEDTAAELELKARVFHFGEYKGDQQDKLLESLNCKVLDVYRHCTGTQQEANLGTVQMLTIIEHQLDELLENLEHVPQVKIEQAERAKEKERRIRLREEKLQMQKILQEEHLQRARARAQAEIKKKRGRTLVCRSRPPAHRIKQQSEHTLMDKEEEELLFFFT
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分子量
97.5 KDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CCDC37, or Coiled-Coil Domain Containing 37, is a protein that plays a vital role in various cellular processes, including protein stabilization and regulation of protein interactions. Recent studies have highlighted its involvement in the assembly of protein complexes, particularly in the context of molecular chaperones and protein degradation pathways. Given its potential implications in disease mechanisms, including cancer and neurodegenerative disorders, reconstitution of CCDC37 as a recombinant protein has become a pivotal area of research. Researchers aim to explore its structural characteristics, functional roles, and interaction partners through reconstitution techniques, allowing for a better understanding of its biological significance. The production of CCDC37 in a recombinant form not only facilitates the study of its biochemical properties but also enables high-throughput screening for potential therapeutic targets. By elucidating the mechanisms by which CCDC37 functions within cellular environments, scientists hope to uncover novel insights into its contributions to pathophysiology and its potential as a biomarker or therapeutic target in various diseases. This research, therefore, stands at the intersection of structural biology, biochemistry, and translational medicine, offering a promising avenue for future discoveries in the field of molecular biology.
