Analytical Data
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基因名
CDYL
- Application
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别名
CDY-like; CDY-like autosomal; Cdyl; CDYL: chromodomain Protein Y-like; CDYL1; CDYL1_HUMAN; chromodomain Protein Y chromosome-like 6; Chromodomain Protein Y like; Chromodomain Y-like Protein; DKFZP586C1622; MGC131936
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y232
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表达区间
1-598
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氨基酸序列
MTFQASHRSA WGKSRKKNWQ YEGPTQKLFL KRNNVSAPDG PSDPSISVSS EQSGAQQPPA LQVERIVDKR KNKKGKTEYL VRWKGYDSED DTWEPEQHLV NCEEYIHDFN RRHTEKQKES TLTRTNRTSP NNARKQISRS TNSNFSKTSP KALVIGKDHE SKNSQLFAAS QKFRKNTAPS LSSRKNMDLA KSGIKILVPK SPVKSRTAVD GFQSESPEKL DPVEQGQEDT VAPEVAAEKP VGALLGPGAE RARMGSRPRI HPLVPQVPGP VTAAMATGLA VNGKGTSPFM DALTANGTTN IQTSVTGVTA SKRKFIDDRR DQPFDKRLRF SVRQTESAYR YRDIVVRKQD GFTHILLSTK SSENNSLNPE VMREVQSALS TAAADDSKLV LLSAVGSVFC CGLDFIYFIR RLTDDRKRES TKMAEAIRNF VNTFIQFKKP IIVAVNGPAI GLGASILPLC DVVWANEKAW FQTPYTTFGQ SPDGCSTVMF PKIMGGASAN EMLLSGRKLT AQEACGKGLV SQVFWPGTFT QEVMVRIKEL ASCNPVVLEE SKALVRCNMK MELEQANERE CEVLKKIWGS AQGMDSMLKY LQRKIDEF
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分子量
66.4 KDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
CDYL (Cancer/Developmental Protein with a C2H2 Zinc Finger) is a protein implicated in various biological processes, including gene regulation and chromatin remodeling. Its involvement in cancer development and progression has garnered significant research interest, as aberrations in CDYL expression and function have been associated with several types of tumors. The protein acts as a critical epigenetic regulator, influencing the expression of genes that control cell growth, differentiation, and apoptosis. As a repressor of transcription, CDYL interacts with chromatin-modifying complexes, thereby participating in the regulation of gene expression networks essential for normal cellular functions and development. Due to its dual roles in both oncogenic and developmental pathways, understanding the structure and function of CDYL is crucial for elucidating its potential as a therapeutic target in cancer. Recent advances in protein expression and purification techniques have facilitated the production of recombinant CDYL, allowing researchers to conduct in-depth studies on its molecular mechanisms, interactions with DNA and other proteins, and its role in malignancies. Investigating recombinant CDYL provides insights that could lead to novel strategies for cancer treatment by modulating its activity or mimicking its function, offering a promising avenue for future therapeutic interventions.
