Analytical Data
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基因名
SLC25A42
- Application
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别名
SLC25A42; Mitochondrial coenzyme A transporter SLC25A42; Solute carrier family 25 member 42
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q86VD7
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表达区间
1-318 aa
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氨基酸序列
MGNGVKEGPVRLHEDAEAVLSSSVSSKRDHRQVLSSLLPGALAGALAKTAVAPLDRTKIIFQVSSKRFSAKEAFRVLYYTYLNEGFLSLWRGNSATMVRVVPYAAIQFSAHEEYKRILGSYYGFRGEALPPWPRLFAGALAGTTAASLTYPLDLVRARMAVTPKEMYSNIFHVFIRISREEGLKTLYHGFMPTVLGVIPYAGLSFFTYETLKSLHREYSGRRQPYPFERMIFGACAGLIGQSASYPLDVVRRRMQTAGVTGYPRASIARTLRTIVREEGAVRGLYKGLSMNWVKGPIAVGISFTTFDLMQIMLRHLQS
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分子量
61.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
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Protein Description
SLC25A42, a member of the solute carrier family 25, is a mitochondrial transporter that plays a crucial role in cellular metabolism, particularly in the transport of essential metabolites across the mitochondrial membrane. Recent studies have indicated that SLC25A42 is involved in various physiological processes, including ATP production and the regulation of calcium homeostasis, which are vital for maintaining cellular energy balance and overall cell function. Dysregulation of this transporter has been linked to several metabolic disorders, highlighting its potential as a therapeutic target. However, the functional mechanisms of SLC25A42 remain poorly understood due to the challenges associated with studying integral membrane proteins. To address this gap, researchers have focused on the production of recombinant SLC25A42 proteins. By employing techniques such as heterologous expression systems, scientists aim to purify and characterize this protein to elucidate its transport mechanisms and interactions with other mitochondrial components. Such studies promise to enhance our understanding of SLC25A42's role in mitochondrial function and its implications in metabolic disease, paving the way for potential biomarker development and targeted therapies in related disorders.
