Analytical Data
-
基因名
SNAPC3
- Application
-
别名
SNAPC3; SNAP50snRNA-activating protein complex subunit 3; SNAPc subunit 3; Proximal sequence element-binding transcription factor subunit beta; PSE-binding factor subunit beta; PTF subunit beta; Small nuclear RNA-activating complex polypeptide 3; snRNA-activating protein complex 50 kDa subunit; SNAPc 50 kDa subunit
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q92966
-
表达区间
1-411 aa
-
氨基酸序列
MAEGSRGGPT CSGVGGRQDP VSGSGGCNFP EYELPELNTR AFHVGAFGEL WRGRLRGAGD LSLREPPASA LPGSQDSD REDVARDL DCSLEAEL RAVCGLDKLK CLEDGEDPEV IPENTDLVTL GVRKRFLEHR EETITIDRAC RQETFVYEME SHAIGKKPEN SADMIEEGEL ILSVNILYPV IFHKHKEHKP YQTMLVLGSQ KLTQLRDSIR CVSDLQIGGE FSNTPDQAPE HISKDLYKSA FFYFEGTFYN DKRYPECRDL SRTIIEWSES HDRGYGKFQT ARMEDFTFND LCIKLGFPYL YCHQGDCEHV IVITDIRLVH HDDCLDRTLY PLLIKKHWLW TRKCFVCKMY TARWVTNNDS FAPEDPCFFC DVCFRMLHYD SEGNKLGEFL AYPYVDPGTF N
-
分子量
46.7 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
SNAPC3, or SNRNP-ASSOCIATED PROTEIN 3, is a crucial component of the spliceosomal machinery, playing a significant role in the regulation of mRNA splicing, an essential process for gene expression. Its function is primarily associated with the formation of splicing complexes and the interaction with various spliceosomal proteins and RNA molecules. Research into SNAPC3 has gained traction due to its involvement in multiple cellular processes, including gene regulation and signal transduction, as well as its implications in various diseases, including cancer and neurodegenerative disorders. The interest in SNAPC3 is further fueled by studies indicating its potential role as a biomarker for certain pathologies and its involvement in transcription regulation, where it contributes to the stability and processing of pre-mRNA. As a result, the elucidation of SNAPC3's structure, function, and interaction networks has become a focal point in molecular biology and therapeutic research. Techniques such as recombinant protein expression, mutagenesis, and biochemical assays are utilized to study its activity and mechanism, paving the way for understanding its contributions to cellular physiology and disease states. This research not only aims to clarify the biological significance of SNAPC3 but also seeks to explore its viability as a target for future therapeutic interventions in splicing-related diseases.
