Analytical Data
-
Gene name
PGM3
- Application
-
Alternative Names
AGM1; PAGM; Phosphoacetylglucosamine Mutase; Acetylglucosamine Phosphomutase; N-acetylglucosamine-phosphate mutase
-
Species
Mouse
-
Source
E. coli
-
Tag
N-His
-
Purity
Greater than 95% as determined by SDS-PAGE.
-
Uniprot
Q9CYR6
-
Expression Region
Met1~Phe237
-
Molecular Weight
33kDa
-
Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
-
Form
Freeze-dried powder
-
Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
-
Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
PGM3, or Phosphoglucomutase 3, is an enzyme involved in carbohydrate metabolism, playing a crucial role in the interconversion of glucose-1-phosphate and glucose-6-phosphate, both of which are essential precursors in various biosynthetic pathways, including glycogen synthesis and glycolysis. The interest in PGM3 has been amplified due to its association with certain metabolic disorders and immune function regulation. Research has revealed that mutations in the PGM3 gene can lead to immunological diseases and increase susceptibility to infections, highlighting its potential as a therapeutic target. Additionally, PGM3 is implicated in the biosynthesis of nucleotide sugars, which are vital for glycosylation processes in protein synthesis and cellular signaling. Given its significant roles in metabolism and immune response, the study of PGM3 and the production of its recombinant protein are essential for understanding its biological functions and exploring its potential as a biomarker or therapeutic target in metabolic and immunological disorders. By generating and characterizing recombinant PGM3, researchers aim to elucidate its structure-function relationships, paving the way for future studies focused on drug development and the engineering of metabolic pathways to improve human health.
