Analytical Data
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Gene name
IZUMO1R
- Application
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Alternative Names
Folate receptor 4 (Folate receptor delta) (FR-delta) (IZUMO1 receptor protein JUNO) (FOLR4) (JUNO)
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Species
Human
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Source
E. coli
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Tag
N- His
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Purity
Greater than 90% as determined by SDS-PAGE.
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Uniprot
A6ND01
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Expression Region
20-250aa
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Molecular Weight
32.4 kDa
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Endotoxin
< 1.0 EU per μg protein as determined by the LAL method.
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Form
Freeze-dried powder
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Buffer formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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Reconstitution
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- Customization
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Stability Test
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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Storage & Shelf Life
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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Shipping
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
Quality inspection process
Related Products
Protein Description
IZUMO1R, also known as the Izumo sperm-egg fusion protein receptor, is an essential component in the process of fertilization. It plays a critical role in sperm-egg recognition and fusion, facilitating successful reproduction. The research surrounding IZUMO1R has gained significant attention due to its implications in infertility, particularly as abnormalities in IZUMO1R function may lead to reproductive challenges. Recent studies have focused on characterizing the structural and functional properties of this receptor, including its interaction with the Izumo1 protein on sperm. Recombinant IZUMO1R protein has been produced to further explore these interactions and to potentially develop therapeutic strategies for infertility treatments. Understanding the mechanisms underlying IZUMO1R's role could not only enhance our knowledge of fertilization but also inform the development of diagnostic tools and targeted therapies aimed at resolving male and female infertility. This research is particularly crucial given the increasing prevalence of reproductive disorders worldwide. Advances in this area could potentially lead to groundbreaking techniques in assisted reproductive technologies, thus benefiting couples facing challenges in conceiving.
