Cat: PA2000-5282

Recombinant Human OPRD1 Protein,His

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Analytical Data

  • Gene name

    OPRD1

  • Application

    SPRMSTBLIITCELISACELL ASSAYDRUG SCREENING

  • Alternative Names

    OPRD1;OPRD;Delta-type opioid receptor

  • Species

    Human

  • Source

    E. coli

  • Tag

    His tag N-Terminus

  • Purity

    Greater than 90% as determined by SDS-PAGE.

  • Uniprot

    P41143

  • Expression Region

    1-372aa

  • AA Sequence

    MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA

  • Molecular Weight

    41.9 kDa

  • Endotoxin

    < 1.0 EU per μg protein as determined by the LAL method.

  • Form

    Freeze-dried powder

  • Buffer formulation

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • Reconstitution

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • Customization

    Site-directed mutagenesis Custom tag design Custom buffer formulation Custom full-length protein production

  • Stability Test

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • Storage & Shelf Life

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • Shipping

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

Quality inspection process

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Protein Description

OPRD1, or opioid receptor delta 1, is a member of the opioid receptor family, which plays a crucial role in pain modulation, emotional response, and various neurobiological processes. Traditionally known for its significance in the central nervous system, OPRD1 has garnered interest due to its potential therapeutic applications in treating pain and addiction-related disorders. Research on the recombinant OPRD1 protein has accelerated in recent years, enabling scientists to better understand its signaling mechanisms and ligand-binding properties. The ability to produce recombinant OPRD1 facilitates high-throughput screening of potential drug candidates, expanding the possibilities for novel analgesics that could minimize side effects commonly associated with conventional opioids. Moreover, insights from OPRD1 studies may lead to the development of targeted therapies that can modulate the receptor's function without the addictive properties of other opioids. As the global opioid crisis continues to present significant public health challenges, the exploration of OPRD1 and its pathways represents a crucial avenue toward discovering new treatment strategies aimed at alleviating pain and combating addiction while maintaining safety and efficacy. This ongoing research not only enhances our understanding of the receptor's biological roles but also holds promise for innovative pharmacological interventions in the future.

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